Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.700 GeneticVariation disease GWASDB Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. 21909108 2011
Entrez Id: 10050
Gene Symbol: SLC17A4
SLC17A4
0.110 GeneticVariation disease GWASDB Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. 21909108 2011
Entrez Id: 10428
Gene Symbol: CFDP1
CFDP1
0.100 GeneticVariation disease GWASDB Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. 23152477 2012
Entrez Id: 54984
Gene Symbol: PINX1
PINX1
0.100 GeneticVariation disease GWASDB Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. 21909108 2011
Entrez Id: 23034
Gene Symbol: SAMD4A
SAMD4A
0.100 GeneticVariation disease GWASDB Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. 23152477 2012
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
0.700 Biomarker disease RGD In conclusion, we suggest that LDLR mutant rats are a useful novel animal model of hypercholesterolemia and atherosclerosis. 22293196 2012
Entrez Id: 183
Gene Symbol: AGT
AGT
0.600 Therapeutic disease RGD Hypertension and atherosclerosis rats were treated with GPE nanoparticles carrying AGT shRNA. 22977667 2012
Entrez Id: 177
Gene Symbol: AGER
AGER
0.600 Biomarker disease RGD High expression of AGE and RAGE in the livers and arteries of rats with NASH may contribute to the pathogenesis of NASH and early atherosclerosis. 20835270 2010
Entrez Id: 3240
Gene Symbol: HP
HP
0.600 Therapeutic disease RGD Vasoprotective effect of vitamin E: rescue of ethanol-induced atherosclerosis and inflammatory stress in rat vascular wall. 23665315 2013
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.600 Biomarker disease RGD Decreased expression of SIRT1 in artery may be involved in the initiation and development of diabetic atherosclerosis. 21810449 2011
Entrez Id: 857
Gene Symbol: CAV1
CAV1
0.400 Therapeutic disease RGD Xuezhikang, extract of red yeast rice, improved abnormal hemorheology, suppressed caveolin-1 and increased eNOS expression in atherosclerotic rats. 23675421 2013
Entrez Id: 3606
Gene Symbol: IL18
IL18
0.300 Therapeutic disease RGD Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats. 23685195 2013
Entrez Id: 958
Gene Symbol: CD40
CD40
0.300 Biomarker disease RGD Our results suggest that the expression of CD40 and CD40L in the blood cells and the activities of MMP-2 and MMP-9 in plasma were higher in As group than those in Normal group, indicating that they may contribute to the formation of atherosclerosis. 16317521 2006
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
0.300 Therapeutic disease RGD To observe the effect of simvastatin on the expression of high mobility group box-1 protein (HMGB1) and morphology of atherosclerotic plaques in atherosclerotic rats, to ascertain whether HMGB1 plays a role in the preventive mechanism of simvastatin from atherosclerosis (AS). 20519084 2010
Entrez Id: 6403
Gene Symbol: SELP
SELP
0.300 Biomarker disease RGD It was discovered that the binding of fibrinogen and the expression of P-selectin on the platelet increase in atherosclerosis model (Group H) than in that in the control group (Group Z), there were closely interrelated. 22340239 2011
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
0.300 Therapeutic disease RGD Effect of curcumin on permeability of coronary artery and expression of related proteins in rat coronary atherosclerosis heart disease model. 26261622 2015
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.300 Biomarker disease RGD Our results suggest that the expression of CD40 and CD40L in the blood cells and the activities of MMP-2 and MMP-9 in plasma were higher in As group than those in Normal group, indicating that they may contribute to the formation of atherosclerosis. 16317521 2006
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
0.300 Biomarker disease RGD Our results suggest that the expression of CD40 and CD40L in the blood cells and the activities of MMP-2 and MMP-9 in plasma were higher in As group than those in Normal group, indicating that they may contribute to the formation of atherosclerosis. 16317521 2006
Entrez Id: 958
Gene Symbol: CD40
CD40
0.300 Therapeutic disease RGD We aimed to investigate whether atorvastatin influenced the CD40-CD40L pathway in atherosclerosis formation in rats fed a high cholesterol diet. 23984971 2013
Entrez Id: 948
Gene Symbol: CD36
CD36
0.300 Therapeutic disease RGD The addition of arginine has a significant effect on reducing rat atherosclerosis development, which may be attributed to both the down-regulation of CD36 expression in rat aortic endothelial and blood mononuclear cells and the NO pathway. 26003171 2015
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
0.300 Therapeutic disease RGD Regression analysis revealed that the predictor of atherosclerosis was CD40L. 23984971 2013
Entrez Id: 1191
Gene Symbol: CLU
CLU
0.280 Therapeutic disease RGD An oral apoJ peptide renders HDL antiinflammatory in mice and monkeys and dramatically reduces atherosclerosis in apolipoprotein E-null mice. 15961700 2005
Entrez Id: 2147
Gene Symbol: F2
F2
0.260 Therapeutic disease RGD [Effects of n-3 polyunsaturated fatty acids on hemorheology and coagulation in atherosclerotic rats]. 20979870 2010
Entrez Id: 836
Gene Symbol: CASP3
CASP3
0.260 Therapeutic disease RGD Liraglutide attenuates atherosclerosis via inhibiting ER-induced macrophage derived microvesicles production in T2DM rats. 29213335 2017
Entrez Id: 846
Gene Symbol: CASR
CASR
0.240 Biomarker disease RGD Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats. 22527939 2012